
<p>While most cases of the COVID-19 coronavirus have been reported in the U.S. , Europe, and China, the virus is spreading rapidly across the African continent. </p>



<p>The confirmed worldwide cases for the virus have surpassed 200 million with the current figure being at 222,262,640</p>



<p>The death toll continues to rise globally now surpassing 4 million. It is currently at 4,593,598.</p>



<p>The world is currently dealing with a new variant of the virus known as the &#8216;Delta Variant&#8217;. The variant is known to be in over 85 countries globally. </p>



<blockquote class="wp-block-quote"><p>A<em>frica has just marked the continent’s most dire pandemic week ever. But the worst is yet to come as the fast-moving third wave continues to gain speed and new ground. The end to this precipitous rise is still weeks away. Cases are doubling now every 18 days, compared with every 21 days only a week ago. We can still break the chain of transmission by testing, isolating contacts and cases and following key public health measures.”</em> <strong><em><em>said Dr Matshidiso Moeti, World Health Organization (WHO) Regional Director for Africa</em></em></strong> <strong><em>on July 8 2021</em></strong></p></blockquote>



<p>The U.S. leads with 666,627 deaths. Brazil comes second with 583,866. India&#8217;s deaths are at 441,433; Mexico is with 263,470 deaths, and Peru is with 198,523.</p>



<p>China, where the virus originated from, maintains that the country&#8217;s death toll is at 4,634.</p>



<p>The figure of the global recoveries stands at 198,882,734.</p>



<p>The African continent now has a total figure of 8,003,746 confirmed cases of Covid-19, while the death toll stands at 200,275. The continent has made 7,162,070 recoveries. </p>



<p>World Health Organization Regional Director for Africa Matshidiso Moeti said in an online briefing Thursday (1 July) that &#8220;The speed and scale of Africa’s third wave are like nothing we’ve seen before.&#8221;  </p>



<p>&#8220;The continent is on the verge of exceeding its worst week ever in this pandemic,&#8221; Moeti said</p>



<p>Here are the country-wide numbers for Africa:</p>



<figure id="main_table_countries_today" class="wp-block-table"><table><thead><tr><th>Country</th><th>Total<br>Cases</th><th>Total<br>Deaths</th><th>Total<br>Recovered</th></tr></thead><tbody><tr><td>Africa</td><td>8,003,746</td><td>200,275</td><td>7,162,070</td></tr><tr><td>Algeria</td><td>198,313</td><td>5,445</td><td>135,232</td></tr><tr><td>Angola</td><td>48,790</td><td>1,282</td><td>44,054</td></tr><tr><td>Benin</td><td>16,946</td><td>135</td><td>11,890</td></tr><tr><td>Botswana</td><td>162,186</td><td>2,309</td><td>155,403</td></tr><tr><td>Burkina Faso</td><td>13,851</td><td>171</td><td>13,575</td></tr><tr><td>Burundi</td><td>12,585</td><td>38</td><td>773</td></tr><tr><td>Cabo Verde</td><td>36,012</td><td>316</td><td>34,725</td></tr><tr><td>Cameroon</td><td>84,210</td><td>1,357</td><td>80,433</td></tr><tr><td>CAR</td><td>11,296</td><td>100</td><td>6,859</td></tr><tr><td>Chad</td><td>4,996</td><td>174</td><td>4,816</td></tr><tr><td>Comoros</td><td>4,086</td><td>147</td><td>3,909</td></tr><tr><td>Congo</td><td>13,588</td><td>183</td><td>12,421</td></tr><tr><td>Djibouti</td><td>11,785</td><td>157</td><td>11,592</td></tr><tr><td>DRC</td><td>55,307</td><td>1,061</td><td>30,858</td></tr><tr><td>Egypt</td><td>290,395</td><td>16,801</td><td>242,623</td></tr><tr><td>Equatorial Guinea</td><td>9,939</td><td>129</td><td>8,971</td></tr><tr><td>Eritrea</td><td>6,648</td><td>38</td><td>6,601</td></tr><tr><td>Eswatini</td><td>44,234</td><td>1,156</td><td>38,871</td></tr><tr><td>Ethiopia</td><td>316,174</td><td>4,785</td><td>284,895</td></tr><tr><td>Gabon</td><td>26,177</td><td>168</td><td>25,775</td></tr><tr><td>Gambia</td><td>9,789</td><td>328</td><td>9,379</td></tr><tr><td>Ghana</td><td>121,307</td><td>1,069</td><td>113,267</td></tr><tr><td>Guinea</td><td>29,877</td><td>358</td><td>27,742</td></tr><tr><td>Guinea-Bissau</td><td>5,902</td><td>121</td><td>4,967</td></tr><tr><td>Ivory Coast</td><td>57,056</td><td>477</td><td>54,804</td></tr><tr><td>Kenya</td><td>241,134</td><td>4,800</td><td>229,762</td></tr><tr><td>Lesotho</td><td>14,395</td><td>403</td><td>6,830</td></tr><tr><td>Liberia</td><td>5,459</td><td>148</td><td>2,715</td></tr><tr><td>Libya</td><td>318,069</td><td>4,363</td><td>230,995</td></tr><tr><td>Madagascar</td><td>42,884</td><td>957</td><td>41,311</td></tr><tr><td>Malawi</td><td>60,852</td><td>2,217</td><td>49,374</td></tr><tr><td>Mali</td><td>14,942</td><td>542</td><td>14,135</td></tr><tr><td>Mauritania</td><td>34,297</td><td>737</td><td>31,832</td></tr><tr><td>Mauritius</td><td>11,466</td><td>32</td><td>1,854</td></tr><tr><td>Mayotte</td><td>19,925</td><td>175</td><td>2,964</td></tr><tr><td>Morocco</td><td>886,008</td><td>13,145</td><td>828,148</td></tr><tr><td>Mozambique</td><td>148,054</td><td>1,881</td><td>137,891</td></tr><tr><td>Namibia</td><td>125,772</td><td>3,414</td><td>120,812</td></tr><tr><td>Niger</td><td>5,888</td><td>199</td><td>5,624</td></tr><tr><td>Nigeria</td><td>195,890</td><td>2,556</td><td>184,882</td></tr><tr><td>Rwanda</td><td>90,145</td><td>1,134</td><td>45,362</td></tr><tr><td>Réunion</td><td>50,346</td><td>342</td><td>47,752</td></tr><tr><td>Saint Helena</td><td>2</td><td></td><td>2</td></tr><tr><td>Sao Tome and Principe</td><td>2,692</td><td>37</td><td>2,461</td></tr><tr><td>Senegal</td><td>73,257</td><td>1,812</td><td>64,582</td></tr><tr><td>Seychelles</td><td>20,323</td><td>108</td><td>19,767</td></tr><tr><td>Sierra Leone</td><td>6,374</td><td>121</td><td>4,364</td></tr><tr><td>Somalia</td><td>17,947</td><td>1,005</td><td>8,896</td></tr><tr><td>South Africa</td><td>2,824,063</td><td>83,617</td><td>2,599,667</td></tr><tr><td>South Sudan</td><td>11,526</td><td>120</td><td>11,195</td></tr><tr><td>Sudan</td><td>37,715</td><td>2,837</td><td>31,675</td></tr><tr><td>Tanzania</td><td>1,367</td><td>50</td><td>183</td></tr><tr><td>Togo</td><td>22,625</td><td>197</td><td>17,669</td></tr><tr><td>Tunisia</td><td>675,191</td><td>23,846</td><td>639,708</td></tr><tr><td>Uganda</td><td>120,714</td><td>3,061</td><td>95,679</td></tr><tr><td>Western Sahara</td><td>10</td><td>1</td><td>8</td></tr><tr><td>Zambia</td><td>207,294</td><td>3,620</td><td>202,500</td></tr><tr><td>Zimbabwe</td><td>125,671</td><td>4,493</td><td>117,036</td></tr></tbody></table><figcaption><a href="https://www.worldometers.info/coronavirus/">Data From World O Meter</a></figcaption></figure>



<p><em>Note: The numbers will be updated as new information is available. </em></p>


South African truck drivers receive COVID-19 vaccine

[IN NUMBERS] Coronavirus Update: COVID-19 In Africa


<p><strong>TOPLINE</strong>: Top infectious disease official Dr. Anthony Fauci on Thursday highlighted the importance of the U.S. quickly gaining control of the delta variant, warning continued community spread could lead to even more dangerous mutations of Covid-19, including those capable of evading the protection of vaccines.</p>



<h2 id="h-key-facts">KEY FACTS</h2>



<p>“That will happen, George, if we don’t get good control over the community spread,” Fauci told “Good Morning America” anchor George Stephanopoulos during a Thursday interview on ABC News.&nbsp;</p>



<p>Allowing the virus to spread through unvaccinated populations—as it is&nbsp;<a href="https://www.forbes.com/sites/nicholasreimann/2021/08/03/florida-shatters-record-for-covid-hospitalization-again-as-desantis-downplays-crisis/">doing</a>&nbsp;<a href="https://www.forbes.com/sites/nicholasreimann/2021/07/31/us-reports-almost-200000-new-covid-cases-in-worst-spike-since-january/">rapidly</a>&nbsp;now—gives it “ample opportunity to mutate,” explained President Biden’s top medical advisor.&nbsp;</p>



<p>“You may sooner or later get another variant, and it is possible that that variant might be in some respects worse than the already difficult variant we’re dealing with now,” Fauci said, referencing the delta variant, which experts say is significantly more infectious than other coronavirus strains.</p>



<p>He also emphasized that the virus can mutate regardless of whether people contracting the virus get symptoms.&nbsp;</p>



<p>Vaccines may be effective at preventing serious disease and death with Covid-19’s current mutations, but this may not necessarily be true with future evolutions, Fauci emphasized.&nbsp;</p>



<h2 id="h-chief-critic">CHIEF CRITIC</h2>



<p>“People who say, ‘I don’t want to get vaccinated because it’s me and I’ll worry about me, I’m not having any impact on anybody else,’ that’s just not the case,” Fauci said.&nbsp;</p>



<h2 id="h-tangent">TANGENT&nbsp;</h2>



<p>Fauci’s warning came as Moderna&nbsp;<a href="https://www.reuters.com/business/healthcare-pharmaceuticals/moderna-says-its-covid-19-shot-remains-93-effective-4-6-months-after-second-dose-2021-08-05/" target="_blank" rel="noreferrer noopener">announced</a>&nbsp;Thursday morning its Covid-19 shot is about 93% effective through six months after the second dose. Pfizer in July said the effectiveness of its jab steadily declines to about 84% six months after the final dose. Both vaccine makers have said they expect booster shots to be necessary ahead of the winter season, particularly due to the threat of the delta variant.&nbsp;</p>



<h2 id="h-key-background">KEY BACKGROUND&nbsp;</h2>



<p>The delta variant is driving surges in Covid-19 cases and hospitalizations that haven’t been seen since the early stages of the U.S.’s vaccine rollout. More than 51,000 Americans are now hospitalized with Covid-19, an 87% increase from two weeks ago, and cases have increased 131% to a daily average of nearly 100,000 during the same period, according to data&nbsp;<a href="https://www.nytimes.com/interactive/2021/us/covid-cases.html" target="_blank" rel="noreferrer noopener">compiled by The New York Times</a>. Deaths have also shot up (by 65%) over the past two weeks, but—at 410—are still well below the country’s winter peak. Fauci has said while it’s “unquestionable” the delta variant is more infectious, it is “less clear” whether it actually causes more serious disease.&nbsp;</p>



<h2 id="h-what-to-watch-for">WHAT TO WATCH FOR&nbsp;</h2>



<p>Fauci warned in an <a href="https://www.mcclatchydc.com/news/coronavirus/article253248688.html" target="_blank" rel="noreferrer noopener">interview</a> with McClatchy on Wednesday the U.S. could begin reporting between 100,000 and 200,000 new cases each day if safety precautions and vaccinations don’t increase. “Remember, just a couple of months ago, we were having about 10,000 cases a day,” Fauci said. There are hopeful signs: After months of decline, the number of Americans getting the shot has been steadily increasing. White House Covid-19 data director Cyrus Shahpar <a href="https://twitter.com/cyrusshahpar46/status/1422226019260370947" target="_blank" rel="noreferrer noopener">announced</a> Tuesday, as the U.S. surpassed a 70% partial inoculation rate, that the seven-day average of newly vaccinated people (441,000) was the highest in more than a month.</p>



<p><em><strong>By Jemima McEvoy, Forbes Staff</strong></em></p>


Dr. Fauci Testifies To Senate Health Committee On Country’s COVID-19 Response

Fauci: Failure To Control Delta Variant Could Lead To ‘Worse’ Mutations That Evade Vaccines


<p><strong>TOPLINE</strong>: The U.S. Food &amp; Drug Administration has extended the shelf life of the Johnson &amp; Johnson single-dose Covid-19 vaccine from four-and-a-half months to six months, the drugmaker announced on Thursday, a decision that comes at a time when several health officials expressed concerns about vaccine doses expiring and going to waste.</p>



<h3 id="h-key-facts">KEY FACTS</h3>



<p>According to a&nbsp;<a href="https://www.jnj.com/johnson-johnson-statement-on-u-s-fda-approval-of-shelf-life-extension-for-companys-covid-19-vaccine" target="_blank" rel="noreferrer noopener">press release</a>&nbsp;by Johnson &amp; Johnson, the FDA’s decision was based on data from ongoing studies that showed the vaccine remains stable when refrigerated at 36 to 46 degrees Fahrenheit.</p>



<p>In a letter sent to the company, the FDA&nbsp;<a href="https://bit.ly/3zRuTMB" target="_blank" rel="noreferrer noopener">noted</a>&nbsp;that the extension will apply to batches that might have expired prior to the issuance of the order as long as they were stored at the requisite temperature.</p>



<p>The company will update the expiry dates of its batches on its&nbsp;<a href="https://vaxcheck.jnj/" target="_blank" rel="noreferrer noopener">website</a>, which vaccine providers can use as a reference.</p>



<p>The move will provide health workers six additional weeks to administer millions of doses of the single-shot vaccine.</p>



<p>The FDA had&nbsp;<a href="https://apnews.com/article/joe-biden-coronavirus-vaccine-science-coronavirus-pandemic-business-6d04574617b35c56e7ca2c711cc5585f" target="_blank" rel="noreferrer noopener">previously extended</a>&nbsp;the J&amp;J vaccine’s shelf life from three months to four-and-half months in June.</p>



<h3 id="h-big-number">BIG NUMBER</h3>



<p>49.3%. That’s the total percentage of people in the U.S. who have been fully vaccinated against Covid-19,&nbsp;<a href="https://covid.cdc.gov/covid-data-tracker/#vaccinations" target="_blank" rel="noreferrer noopener">according to</a>&nbsp;the Centers for Disease Control (CDC) and Prevention. Among U.S. adults, 69.3% of people have received at least one dose of the vaccine.</p>



<h3 id="h-key-background">KEY BACKGROUND</h3>



<p>Unlike the two mRNA Covid-19 vaccines—made by Moderna and Pfizer—J&amp;J’s vaccine is administered as a single shot and can be stored in normal refrigeration temperatures. This means that the vaccine can be easily transported and administered in rural and isolated parts of the country where healthcare infrastructure may be limited.&nbsp;<a href="https://covid.cdc.gov/covid-data-tracker/#vaccinations" target="_blank" rel="noreferrer noopener">According to</a>&nbsp;the CDC, more than 13 million people in the U.S. have received the one-shot vaccine. In comparison, more than 87 million people have received two doses of the Pfizer vaccine and 63 million have received two jabs of the Moderna vaccine.</p>



<h3 id="h-further-reading">FURTHER READING</h3>



<p><a href="https://apnews.com/article/business-science-health-coronavirus-pandemic-coronavirus-vaccine-8126286b2c8bc65970117a08c77af075" target="_blank" rel="noreferrer noopener">US extends expiration dates on J&amp;J COVID vaccine to 6 months</a>&nbsp;(Associated Press)</p>



<p><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/us-fda-agrees-extend-jj-covid-19-vaccines-shelf-life-6-months-2021-07-28/" target="_blank" rel="noreferrer noopener">J&amp;J says U.S. FDA agrees to extend shelf life of its COVID-19 vaccine</a>&nbsp;(Reuters)</p>



<p><a href="https://www.nytimes.com/2021/07/28/world/johnson-vaccine-shelf-life.html" target="_blank" rel="noreferrer noopener">J&amp;J vaccine shelf life extended to six months by F.D.A.</a> (New York Times)</p>



<p><strong><em>By Siladitya Ray, Forbes Staff</em></strong></p>


A health worker holds a vial of Janssen vaccine (American

FDA Extends Shelf Life Of Johnson & Johnson Covid-19 Vaccine To Six Months


<p><strong>TOPLINE</strong> A new study out of South Korea found that taking an AstraZeneca vaccine shot followed by a Pfizer-BioNTech vaccine shot boosted Covid-19 antibody levels six times more than receiving two Astra-Zeneca doses, as some governments around the world are giving the green light to mix Covid-19 vaccine shots for extra protection against the virus.</p>



<h3 id="h-key-facts">KEY FACTS</h3>



<p>The study was conducted by the Korea Disease Control and Prevention Agency, and it took a look at the effects of mixing certain vaccine doses and vaccine efficacy against coronavirus variants Alpha, Beta, Gamma and Delta, as first&nbsp;<a href="https://www.reuters.com/business/healthcare-pharmaceuticals/mixed-astrazeneca-pfizer-shot-boosts-covid-antibody-level-study-2021-07-26/" target="_blank" rel="noreferrer noopener">reported</a>&nbsp;by Reuters.</p>



<p>About 499 medical workers took part in the study, with about 200 workers receiving two doses of the AstraZeneca vaccine, 200 workers receiving two doses of the Pfizer-BioNTech vaccine and 100 workers receiving mixed doses of both the vaccines.</p>



<p>All three groups acquired antibodies, with the group that mixed AstraZeneca and Pfizer showing similar levels of antibodies as the group that received the two Pfizer shots.&nbsp;</p>



<p>The study also found that each of the vaccine doses were most effective against the Alpha variant, but&nbsp; showed decreased effectiveness between 2 ½ to 6 times on Beta, Gamma and Delta variants.</p>



<h3 id="h-key-background">KEY BACKGROUND</h3>



<p>Back in June, Oxford University led a&nbsp;<a href="https://www.forbes.com/sites/jemimamcevoy/2021/06/28/uk-study-offers-new-evidence-you-can-mix-and-match-coronavirus-vaccines/?sh=64cc30081082">study</a>&nbsp;to find out if mixing and matching vaccines was viable. It found that taking an AstraZeneca vaccine shot followed by a Pfizer shot created the highest T-cell response, which are immune cells that attack and destroy infected cells. The vaccine combo also generated more antibodies than taking a Pfizer shot followed by an AstraZeneca shot. Both the Oxford University study and Korea Disease Control and Prevention Agency study show that vaccines can still provide a strong immunity response to the virus if mixed and matched. The United States&nbsp;<a href="https://www.cdc.gov/vaccines/covid-19/clinical-considerations/covid-19-vaccines-us.html" target="_blank" rel="noreferrer noopener">Centers for Disease Control</a>&nbsp;does not recommend mixing doses from different vaccines since it has not yet evaluated if that practice is safe and effective. However, some countries like Germany and Spain allow for mixed shots, allowing people to receive Pfizer and Moderna shots even after they have already gotten AstraZeneca’s first dose. Canada’s health officials also started to&nbsp;<a href="https://www.cbc.ca/news/health/canada-mixing-covid-19-vaccines-astrazeneca-pfizer-moderna-naci-1.6048152" target="_blank" rel="noreferrer noopener">recommend&nbsp;</a>mixing vaccine shots last month, if people are unable to take two of the same vaccine doses.</p>



<h3 id="h-tangent">TANGENT</h3>



<p>As the Delta variant continues to grow internationally, more people are reporting taking multiple vaccine doses. Chancellor of Germany Angela Merkel&nbsp;<a href="https://www.bbc.com/news/world-europe-57571791" target="_blank" rel="noreferrer noopener">received</a>&nbsp;the Moderna jab at the end of June, a few months after she received her first AstraZeneca shot. One U.S. doctor received the one-shot Johnson &amp; Johnson vaccine in Seattle, but then, after moving to Canada, got one shot of the Pfizer vaccine for added protection, according to a&nbsp;<a href="https://www.cnbc.com/2021/07/26/delta-people-are-mixing-and-matching-covid-vaccines-over-concerns-about-variant.html" target="_blank" rel="noreferrer noopener">report</a>&nbsp;by CNBC. The U.S. does not consider people who have had different doses of vaccines as fully vaccinated.</p>



<h3 id="h-what-to-watch-out-for">WHAT TO WATCH OUT FOR</h3>



<p>Pfizer said it will be creating a&nbsp;<a href="https://www.cnbc.com/2021/07/08/pfizer-says-it-is-developing-a-covid-booster-shot-to-target-the-highly-transmissible-delta-variant.html" target="_blank" rel="noreferrer noopener">booster</a>&nbsp;shot to target the Delta variant. Trials for the booster shot&nbsp;<a href="https://www.wsmv.com/news/pfizer-booster-shot-trial-underway-in-nashville/article_5447ab60-edf5-11eb-b977-6b315cb7c729.html" target="_blank" rel="noreferrer noopener">began</a>&nbsp;in Nashville on Monday. Moderna also announced it will be developing a booster shot, with&nbsp;<a href="https://www.cbsnews.com/news/covid-19-vaccine-booster-shot-what-we-know/" target="_blank" rel="noreferrer noopener">trial</a>&nbsp;results expected by September. Some doctors are even&nbsp;<a href="https://www.cnbc.com/2021/07/20/dr-vin-gupta-encourages-jj-vaccine-recipients-to-get-a-pfizer-or-moderna-booster.html" target="_blank" rel="noreferrer noopener">encouraging</a>&nbsp;those who received the Johnson &amp; Johnson vaccine to consider getting either a Pfizer or Moderna booster shot, even though it is unclear how the booster shots may work with other vaccines.</p>



<h3 id="h-further-reading">FURTHER READING</h3>



<p><a href="https://www.forbes.com/sites/jemimamcevoy/2021/06/28/uk-study-offers-new-evidence-you-can-mix-and-match-coronavirus-vaccines/?sh=64cc30081082">U.K. Study Offers New Evidence You Can ‘Mix And Match’ Coronavirus Vaccines</a>&nbsp;(<em>Forbes</em>)</p>



<p><a href="http://mymusictaste.com/artist/68f14b7dcc835375b53d0ea65f4dedd7/" target="_blank" rel="noreferrer noopener">Americans are ‘mixing and matching’ Covid vaccines over concerns about the delta variant</a> (<em>CNBC</em>)</p>



<p><strong><em>By Kimberlee Speakman, Forbes Staff</em></strong></p>


Dept of Correctional Services Vaccination Rollout Launch in South Africa

Mixed AstraZeneca-Pfizer Vaccine Boosts Covid Antibody Levels, Korea Study Finds


<p><strong>TOPLINE</strong>: The Chinese government on Thursday rejected the World Health Organisation’s plan for the second phase of investigation into the origins of Covid-19—which will also examine the possibility that the virus may have escaped from a Wuhan lab—signaling further politicization of the investigation that has previously been hampered by Beijing’s unwillingness to share important data.</p>



<h3 id="h-key-facts">KEY FACTS</h3>



<p>Zeng Yixin, the vice minister of China’s National Health Commission (NHC), told reporters he was “shocked” by the plan to investigate the lab leak hypothesis and said “it is impossible for us to accept such an origin-tracing plan.”</p>



<p><a href="https://apnews.com/article/health-china-coronavirus-pandemic-united-nations-a20391afec60601f3d666efc3c18b61d" target="_blank" rel="noreferrer noopener">According to</a>&nbsp;the Associated Press, Zeng dismissed the theory as a rumor “that runs counter to common sense and science.”</p>



<p>Responding to the WHO’s earlier statement about the investigation being hampered by the lack of raw data from Chinese authorities, Zeng reiterated Beijing’s stance that some data could not be completely shared due to privacy concerns.</p>



<p>Zeng insisted that the Wuhan Institute of Virology’s labs have no virus that can directly infect humans and noted that a WHO-led team of experts had visited the lab earlier this year and concluded that a leak was highly unlikely.</p>



<p>The vice minister also dismissed&nbsp;<a href="https://www.wsj.com/articles/intelligence-on-sick-staff-at-wuhan-lab-fuels-debate-on-covid-19-origin-11621796228?reflink=share_mobilewebshare" target="_blank" rel="noreferrer noopener">media reports</a>&nbsp;that staff and graduate students at the institute had fallen sick due to the virus and then transmitted it to others.</p>



<p>The vocal push back from Beijing comes a week after WHO Director-General Tedros Adhanom Ghebreyesus called for better cooperation from China and&nbsp;<a href="https://apnews.com/article/joe-biden-world-news-health-science-coronavirus-pandemic-c0c594f9060f676c0ea48c2d1c69daec" target="_blank" rel="noreferrer noopener">noted</a>&nbsp;that there had been a “premature push” to rule out the lab leak theory.</p>



<h3 id="h-key-background">KEY BACKGROUND</h3>



<p>In March, the World Health Organization and China&nbsp;<a href="https://www.who.int/publications/i/item/who-convened-global-study-of-origins-of-sars-cov-2-china-part" target="_blank" rel="noreferrer noopener">published</a>&nbsp;a joint study that offered preliminary insight into the origin of the SARS-CoV2 coronavirus. The report suggested that the outbreak was likely caused by the virus jumping from bats to humans through an intermediary animal and also labeled the lab leak hypothesis as “extremely unlikely.” It was&nbsp;<a href="https://www.theguardian.com/world/2021/mar/30/who-criticises-chinas-data-sharing-as-it-releases-covid-origins-report" target="_blank" rel="noreferrer noopener">sharply criticized</a>&nbsp;by the U.S., U.K., Canada and several other countries who accused China of “withholding access to complete original data and samples”. The lab leak theory—initially pushed by fringe groups—has seen a rise in mainstream interest after President Joe Biden&nbsp;<a href="https://www.forbes.com/sites/jackbrewster/2021/05/26/biden-says-intelligence-agencies-have-coalesced-around-two-likely-scenarios-for-origin-of-covid-19/?sh=266488003fb2">ordered</a>&nbsp;U.S. intelligence agencies to examine the origin of the pandemic in May. U.S. intelligence agencies have two prevailing theories at the moment with branches believing that it was transmitted from animals, while another branch believes it came from a lab at the Wuhan Institute of Virology, which does research work on bat viruses.</p>



<h3 id="h-further-reading">FURTHER READING</h3>



<p><a href="https://apnews.com/article/health-china-coronavirus-pandemic-united-nations-a20391afec60601f3d666efc3c18b61d" target="_blank" rel="noreferrer noopener">China rebuffs WHO’s terms for further COVID-19 origins study</a>&nbsp;(Associated Press)</p>



<p><a href="https://www.reuters.com/world/china/china-will-not-follow-whos-suggested-plan-2nd-phase-covid-19-origins-study-2021-07-22/" target="_blank" rel="noreferrer noopener">China rejects WHO plan for study of COVID-19 origin</a> (Reuters)</p>



<p><em><strong>By Siladitya Ray, Forbes Staff</strong></em></p>


News Conference On Chinese Vaccines Against COVID-19 In Beijing

China ‘Shocked’ By WHO’s Plan To Investigate Covid-19 Lab Leak Theory


<p><strong>TOPLINE</strong> Both the Pfizer and AstraZeneca coronavirus vaccines work well at preventing symptomatic cases of the delta coronavirus variant—which became the dominant strain in the U.S. this month—but the vaccines’ effectiveness drops significantly in patients who only have one of the two doses, according to a new study.</p>



<h3 id="h-key-facts">KEY FACTS</h3>



<p>A study of 19,000 people from&nbsp;<a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2108891" target="_blank" rel="noreferrer noopener">Public Health England</a>&nbsp;published Wednesday found that both doses of either the Pfizer or AstraZeneca vaccines help protect against symptoms from both the alpha (B.1.1.7, also known as&nbsp;<a href="https://www.forbes.com/sites/carlieporterfield/2021/04/07/uk-coronavirus-variant-is-now-the-dominant-strain-in-us-cdc-says/">the U.K. variant</a>) and delta variants at comparable rates.</p>



<p>Two doses of the Pfizer vaccine had an effectiveness of 93.7% at preventing symptomatic alpha infections, and 88% for the delta variant.</p>



<p>Two doses of AstraZeneca were found to be 74.5% effective at preventing symptomatic alpha infections, and 67% for delta.</p>



<p>However, the effectiveness of the vaccines plummeted if a patient had only received one dose of either vaccine: the study found both to be just more than 48% effective against alpha and only about 30% effective against delta.</p>



<p>Researchers said their findings support the theory that&nbsp;<a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2108891" target="_blank" rel="noreferrer noopener">prioritizing second doses</a>, especially in vulnerable populations, is an effective way to prevent coronavirus outbreaks.&nbsp;</p>



<h3 id="h-tangent">TANGENT</h3>



<p>The single-dose Johnson &amp; Johnson vaccine only has&nbsp;<a href="https://www.forbes.com/sites/nicholasreimann/2021/07/20/johnson--johnson-vaccine-far-less-effective-against-delta-variant-study-suggests/?sh=44f5e2864299">a 33% efficacy rate</a>&nbsp;against the delta variant, a New York University study released Tuesday suggested, although it has not been peer reviewed.&nbsp;A small study from Moderna last month suggested their vaccine also&nbsp;<a href="https://investors.modernatx.com/news-releases/news-release-details/moderna-provides-clinical-update-neutralizing-activity-its-covid" target="_blank" rel="noreferrer noopener">offers protection</a>&nbsp;against the delta strain.</p>



<h3 id="h-key-background">KEY BACKGROUND</h3>



<p>The delta variant, which experts believe is more transmissible than earlier forms of coronavirus, is thought to be the driving force behind <a href="https://www.forbes.com/sites/joewalsh/2021/07/17/covid-hospitalizations-rise-nationwide-amid-delta-surge---especially-in-these-states/?sh=290e647e52a8">a new wave of infections</a> and a jump in hospitalizations across the U.S. Experts have warned about the danger delta could pose. Former Food and Drug Administration head Dr. Scott Gottlieb said the “majority” of unvaccinated Americans would likely contract the delta mutation eventually, adding the disease “is going to be the <a href="https://www.forbes.com/sites/jemimamcevoy/2021/07/18/former-fda-head-says-delta-will-infect-majority-of-unvaccinated-americans-and-may-be-most-serious-virus-in-their-lifetime/?sh=22ee15f06b17">most serious virus</a> they will get in their lifetime in terms of the risk of putting them in the hospital.” The surge of new cases has pushed some cities like <a href="https://www.forbes.com/sites/graisondangor/2021/07/15/los-angeles-reportedly-will-reinstate-mask-mandate-saturday/?sh=7b879fb45373">Los Angeles</a> and <a href="https://www.forbes.com/sites/alisondurkee/2021/07/21/delta-fueled-covid-surge-spurs-new-mask-mandates---here-are-the-states-where-they-cant-legally-be-reimposed/?sh=6be7887c37b4">Las Vegas</a> to reintroduce mandatory masking in some indoor spaces.</p>



<p><strong><em>By Carlie Porterfield, Forbes Staff</em></strong></p>


A doctor’s hand with a syringe of covid-19 coronavirus vaccine.

Study Finds Pfizer And AstraZeneca Vaccines Effective Against The Delta Variant — As Long As You Get Both Doses


<p><strong>TOPLINE</strong>: Pfizer has struck a deal with a South African drug manufacturer to begin producing and distributing its coronavirus vaccine in Africa for the first time, the company announced Wednesday, in a move that follows mounting pressure to address inequalities in the global vaccine rollout.</p>



<h3 id="h-key-facts">KEY FACTS</h3>



<p>Pfizer&nbsp;<a href="https://investors.biontech.de/news-releases/news-release-details/pfizer-and-biontech-announce-collaboration-biovac-manufacture" target="_blank" rel="noreferrer noopener">said</a>&nbsp;it will be working with South Africa’s Biovac Institute, a public-private partnership focused on vaccine production, to produce and distribute over 100 million doses a year for the African Union beginning in 2022.&nbsp;</p>



<p>Biovac will be shipped batches of vaccine ingredients from Europe and then will perform so-called fill and finish operations, the last stage of manufacturing and packaging, according to a press release from the company.&nbsp;</p>



<p>Though technical transfer, on-site development and equipment installation activities will begin immediately, the company said manufacturing of the finished doses will only begin in 2022.&nbsp;</p>



<p>“At full operational capacity, the annual production will exceed 100 million finished doses annually,” which will be distributed within the 55 member states making up the African Union, the company said.&nbsp;</p>



<h3 id="h-crucial-quotes">CRUCIAL QUOTES</h3>



<p>Pfizer CEO Andrew Bourla, who is set to give a speech later Wednesday at the World Trade Organization Summit, deemed the partnership progress toward the company’s goal of providing “fair and equitable” access to the vaccine “to everyone, everywhere.” Meanwhile, Biovac CEO Dr. Morena Makhoana lauded it as a “critical step forward.” “We believe this collaboration will create opportunity to more broadly distribute vaccine doses to people in harder-to-reach communities, especially those on the African continent,” said Makhoana.&nbsp;</p>



<h3 id="h-key-background">KEY BACKGROUND&nbsp;</h3>



<p>The pace of vaccinations in Africa is running far behind the rest of the world. Just over 1.5% of Africans have been fully vaccinated, according to the Africa Centers for Disease Control and Prevention, making the continent’s goal of having 20% of its population vaccinated by the end of 2021 increasingly unlikely. This is largely due to a lack of African-based vaccine manufacturing facilities. The continent was relying on the World Health Organization-backed COVAX effort for its doses. However, COVAX has fallen far behind schedule, having delivered only 200 million doses since February (the U.S. has administered 338 million), in part because of the troubles of its biggest supplier, the Serum Institute of India.&nbsp;</p>



<h3 id="h-what-to-watch-for">WHAT TO WATCH FOR&nbsp;</h3>



<p>Africa’s rollout is lagging at a time when the more infectious delta variant is driving a record surge of cases. Earlier this month, the continent reported its&nbsp;<a href="https://www.nytimes.com/2021/07/08/world/africa-coronavirus-cases-who.html" target="_blank" rel="noreferrer noopener">“worst pandemic week ever”</a>&nbsp;after 16 countries saw a resurgence in infections, amounting to over 250,000 cases reported in just one week.&nbsp;</p>



<h3 id="h-further-reading">FURTHER READING&nbsp;</h3>



<p><a href="https://www.nytimes.com/interactive/2021/07/16/world/africa/africa-vaccination-rollout.html" target="_blank" rel="noreferrer noopener">“Africa’s Covid Crisis Deepens, but Vaccines Are Still Far Off”</a> (The New York Times)</p>



<p><em><strong>By Jemima McEvoy, Forbes Staff</strong></em></p>


US-HEALTH-VIRUS-VACCINE

Pfizer Strikes Deal To Produce Vaccines In Africa As Continent Falls Far Behind In Covid Fight


<p><strong>Tom Bennett, Director and Founder of researchEd in the United Kingdom, on what evidence tells us about the future and purpose of education.</strong></p>



<p class="has-text-align-center"><strong><em>BY JILL DE VILLIERS</em></strong></p>



<p>AS COVID-19 SWEPT THROUGH THE WORLD, SOME AREAS OF OUR lives were more deeply affected than others, one of them being education. Before the pandemic, technology had started taking a more prominent place in education, and online learning was being integrated into the system. </p>



<p>When Covid-19 struck, schools and tertiary institutions were forced to change their models rapidly, migrating to digital options. Soon, the talk pivoted to blended learning and hybrid solutions, combining in-person and virtual classrooms and teaching methods. How likely are we to return to old teaching methods and classroom settings, we ask educationist, author and speaker Tom Bennett, who hails from the United Kingdom (UK) and is the Director and Founder of researchED. </p>



<div class="wp-block-media-text alignwide is-stacked-on-mobile" style="grid-template-columns:34% auto"><figure class="wp-block-media-text__media"><img decoding="async" loading="lazy" width="768" height="1024" src="https://cms.forbesafrica.com/wp-content/uploads/2021/06/Tom-Bennett_1-768x1024.jpg" alt="" class="wp-image-51596 size-full" srcset="https://cms.forbesafrica.com/wp-content/uploads/2021/06/Tom-Bennett_1-768x1024.jpg 768w, https://cms.forbesafrica.com/wp-content/uploads/2021/06/Tom-Bennett_1-225x300.jpg 225w, https://cms.forbesafrica.com/wp-content/uploads/2021/06/Tom-Bennett_1-1152x1536.jpg 1152w, https://cms.forbesafrica.com/wp-content/uploads/2021/06/Tom-Bennett_1-1536x2048.jpg 1536w, https://cms.forbesafrica.com/wp-content/uploads/2021/06/Tom-Bennett_1-scaled.jpg 1920w" sizes="(max-width: 768px) 100vw, 768px" /></figure><div class="wp-block-media-text__content">
<blockquote class="wp-block-quote"><p><strong><em>Tom Bennett will deliver a talk during the 2021 Future of Education Virtual Summit, with the theme ‘Redefining the Purpose of Education’ on July 29, held in partnership with FORBES AFRICA and CNBC Africa</em></strong></p></blockquote>
</div></div>



<p>“After Covid, I see education 95% snapping back to where it was before, because the face-toface model of education simply cannot be beaten in most circumstances. The one benefit of the Covid experience has been that people the world over have seen how hard it is to home school children, how much blended learning often lacks compared to face-to-face… but also we have learned remote learning is not something impossible to manage and that where it is useful, we have lost our fear of trying it. For example, in the UK, whenever it snows, schools often shut and nothing gets done. But now, no more snow days, although I’m not sure that children and staff are as happy about that!” Bennett says. </p>



<p>He was a teacher in the East End of London for 13 years before founding researchED, which he describes as “an international non-profit that asks simple questions that can change the world”. The organization brings together everyone within the educational ecosystem – “not just the privileged priest class of education, but teaching assistants, administrators, teachers, as well as academics, leaders and researchers – to share their thoughts about what they do, and what evidence informs what they do.” </p>



<p>They travel the world, presenting low-cost, inclusive and accessible events, which are particularly popular among teaching staff, who are hungry for answers to questions like: ‘How can I achieve what I want, without struggling blindly in the dark? What does the evidence tell me? When do things work, and when do they not work?’ </p>



<p>Bennett has written four books on classroom behavior and evidence-informed education. “Ideas about how we manage behavior are still stuck in the 19th century, and too many teachers and schools are forced to reinvent the wheel every generation instead of building upon what we have found to work and improving upon it,” he explains. </p>



<p>“Teachers rarely get an evidence-informed training as they begin their careers, and many schools still make decisions based on intuition, gut feeling and hunches. But children – and teachers – deserve much better than that. We can do much better than that.” </p>



<p>Lately, we have seen a burgeoning of technology solutions to a myriad of questions that Bennett says teachers aren’t asking. </p>



<p>“Tech companies are often guilty of selling solutions to problems no one has, and ignoring the lack of evidence to back up the boldest of their claims. That’s not to say that tech doesn’t offer enormous opportunities to supplement and support education, but also to say that schools and countries have poured billions into tech promises that have rarely materialized.</p>



<p>“Evidence tells us many things that teachers can incorporate into their classrooms with only a little effort and with huge dividends: low-stakes retrieval practise (frequent testing) secures lesson retention enormously; being aware of cognitive load theory teaches us the students need information presented in manageable chunks, and that teachers should favour direct instruction with novice learners before allowing them too much freedom to drive their own studies. </p>



<p>This is especially relevant with blended forms of learning, where beginning learners often drown in what they don’t know, and might lack the motivation and the foundational knowledge how to drive their own learning at home.” And finally, how does Bennett see the purpose of education? </p>



<p>“The beauty of education is it has no intrinsic purpose. We have purposes for education. So when we ask ‘How should we educate?’ Then we have to first ask, ‘What do we think the aim of this education is for?’ Only once we have answered that can we rationally begin to decide what we need to do, whether we’re trying to teach the best of what has been thought and said, prepare citizens for the future, or help children become fully rounded human beings.&#8221;<br></p>


Focus on raised hands in classroom

Education: What We Can Do Better


<p><strong>TOPLINE</strong>: Both the Pfizer-BioNTech and Moderna vaccines are likely to offer long-lasting protection against Covid-19, according to a study published on Monday, indicating that people who are already inoculated with either of the mRNA vaccines may not need a booster dose for years.</p>



<h3 id="h-key-facts">KEY FACTS</h3>



<p>According to a&nbsp;<a href="https://www.nature.com/articles/s41586-021-03738-2" target="_blank" rel="noreferrer noopener">peer-reviewed study</a>&nbsp;published in the science journal&nbsp;<em>Nature</em>, scientists found that the vaccines induced a strong immune reaction that may protect against Covid-19 for years.</p>



<p>The study reinforces a previous finding,&nbsp;<a href="https://www.nytimes.com/2021/05/26/health/coronavirus-immunity-vaccines.html" target="_blank" rel="noreferrer noopener">first reported in May</a>, that people who have both recovered from infection and have been fully inoculated with one of the mRNA vaccines have an even stronger immune response.</p>



<p>The study also showed that the vaccines produced high levels of neutralizing antibodies that were effective against three variants of the coronavirus, including the Beta variant that has been shown to reduce the effectiveness of vaccines.</p>



<p>Nearly four months after the first dose of either vaccine, the body still had the so-called germinal centers in the lymph nodes which effectively train the body’s immune cells to protect against future infection.</p>



<p>According to scientists who conducted the study, this is a very positive sign since germinal centers normally peak one or two weeks after vaccination and then begin to decline, the New York Times&nbsp;<a href="https://www.nytimes.com/live/2021/06/28/world/covid-vaccine-coronavirus-mask?smtyp=cur&amp;smid=tw-nytimesworld#a-study-finds-that-the-pfizer-and-moderna-vaccines-could-offer-protection-for-years" target="_blank" rel="noreferrer noopener">reported</a>.</p>



<p>Production of a broader range of immune cells and longer training times for those cells will lead to more robust protection against the virus and any variants that may emerge.</p>



<h3 id="h-what-we-don-t-know">WHAT WE DON’T KNOW</h3>



<p>The scope of the study was only limited to the two approved mRNA vaccines manufactured by Moderna and Pfizer-BioNTech. It did not examine the single-dose Johnson &amp; Johnson vaccine and one of the study’s authors&nbsp;<a href="https://www.nytimes.com/live/2021/06/28/world/covid-vaccine-coronavirus-mask?smtyp=cur&amp;smid=tw-nytimesworld#a-study-finds-that-the-pfizer-and-moderna-vaccines-could-offer-protection-for-years" target="_blank" rel="noreferrer noopener">told</a>&nbsp;the&nbsp;<em>New York Times&nbsp;</em>that he expected the immune response from that shot to be less durable. The study also does not throw any light on the effectiveness of the vaccine against the Delta variant of the coronavirus which is more transmissible than other variants.</p>



<h3 id="h-key-background">KEY BACKGROUND</h3>



<p>While the mRNA vaccines have been highly effective in preventing infections, the emergence of more infectious variants of the coronavirus has led to speculation that booster doses may be needed to protect against Covid-19. Speaking at a&nbsp;<em>Forbes</em>&nbsp;event earlier this month, Moderna CEO Stéphane Bancel&nbsp;<a href="https://www.forbes.com/sites/forbesfellows/2021/06/08/moderna-ceo-says-vaccine-boosters-and-flucovid-combo-shots-are-likely-for-the-future/?sh=886c6a03347d">also suggested</a>&nbsp;that it was likely booster shots will be needed in the near future, both to bolster waning immunity and to protect against new virus mutations. However, public health officials, including Dr. Anthony Fauci, have&nbsp;<a href="https://www.latimes.com/science/story/2021-05-21/covid-19-booster-shots-not-necessarily-needed-this-fall-fauci-says" target="_blank" rel="noreferrer noopener">pushed back</a>&nbsp;against this notion. The results of this study suggest that a vast majority of people, who have received one of the two mRNA vaccines, will likely be protected over the long term and may not need a booster shot anytime soon. However, the emergence of newer, more infectious variants could still blunt the effectiveness of these mRNA vaccines. Additionally, a large proportion of vaccine recipients around the world have received viral vector-based vaccines which may offer less durable immunity.</p>



<h3 id="h-further-reading">FURTHER READING</h3>



<p><a href="https://www.nytimes.com/live/2021/06/28/world/covid-vaccine-coronavirus-mask?smtyp=cur&amp;smid=tw-nytimesworld#a-study-finds-that-the-pfizer-and-moderna-vaccines-could-offer-protection-for-years" target="_blank" rel="noreferrer noopener">mRNA Vaccines May Offer Lasting Protection, Study Finds</a>&nbsp;(New York Times)</p>



<p><a href="https://www.nytimes.com/2021/05/26/health/coronavirus-immunity-vaccines.html" target="_blank" rel="noreferrer noopener">Immunity to the Coronavirus May Persist for Years, Scientists Find</a>&nbsp;(New York Times)</p>



<p><em><strong>By Siladitya Ray, Forbes Staff</strong></em></p>


In this photo illustration the medical syringe is seen with

Pfizer And Moderna Vaccines May Offer Years-Long Protection Against Covid-19, Scientists Say


<p><strong>In Africa, the jury is still out on the tradeoff between Covid-19 lockdowns and livelihoods. </strong></p>



<p>Following the outbreak of the Covid-19 pandemic in early 2020, many African governments swiftly implemented broad containment and lockdown measures that helped save many lives but which came at a great cost to economic activity and livelihoods.&nbsp;</p>



<p>This is one of the key conclusions of the African Development Bank’s (AfDB) <em>African Economic Outlook (AEO)</em><em> 2021 </em>report, released on March 12, which critically assesses the costs and benefits of lockdowns. African countries that imposed stringent lockdowns reported lower Covid-19 infection rates, the report finds, after controlling for the use of public information campaigns, testing, and contact tracing policies as well as recurrent shocks that are common across countries, such as weather-related shocks (such as droughts and flooding).</p>



<p><strong>Lockdowns have curbed disease spread in Africa, but less effectively than elsewhere</strong></p>



<p>African countries have been proactive in their responses, taking preventive measures as soon as confirmed Covid-19 cases were reported. Half of African countries with available data restricted international travel through arrival screening, quarantines, bans on arrivals from some or all regions, and even total border closures one day after the first Covid-19 case was detected.&nbsp;</p>



<p>The report indicates that closures of schools, public transport systems, and workplaces, as well as curfews and cancellations of public events, proved more effective in curbing Covid-19 infections than prohibitions on private gatherings and bans on domestic and international travel.</p>



<p>Lockdowns had a more pronounced impact in other regions than across Africa, which saw only modest reductions of about 0.1% in infection cases per thousand after one month, and of about 1% after 60 days. By comparison, using the same approach and data, IMF data from 15 G20 countries found that after a month of lockdowns, Covid-19 cases fell by an estimated 40%.&nbsp;</p>



<p>Why? One explanation is that a significant majority of Africans are engaged in informal activities that do not permit working from home. These informal workers – who are paid daily or weekly, rarely have savings, and lack access to bank loans – are more likely to defy official lockdown measures to safeguard their livelihoods. &nbsp;</p>



<p>The result is that, despite their best efforts, African governments have been unable to impose lockdowns as stringent as those in industrialized nations, where remote working is feasible for a larger share of the population. &nbsp;</p>



<p>Stringent lockdown measures are associated with significant economic contraction, the report finds. In particular, when the index of lockdown stringency increased by one unit, GDP and the industrial production index decreased on average by respectively 0.59% and 0.29% during the first half of 2020 – when the outbreak peaked in Africa – versus the same period in 2019.&nbsp;</p>



<p><strong>A tricky tradeoff?</strong></p>



<p>The pandemic seems to present African countries with a tricky trade-off between saving lives, on the one hand, and protecting economic activity and livelihoods on the other. But this framing is misleading. African countries can successfully pursue both objectives by imposing lockdowns while taking measures to limit the effects of those lockdowns on people’s livelihoods, especially the poor, and on businesses. Finding the right balance between these two aims is crucial.&nbsp;</p>



<p>The AEO recommends a number of policies that could be implemented. For instance, where there is fiscal space or sufficient liquidity, policymakers should maintain fiscal and monetary support to vulnerable people and businesses to enable them to stay afloat. In other countries, international grants and concessional loans can be deployed instead, so long as debt sustainability levels are not exceeded.&nbsp;</p>



<p>Expanding social safety nets to include informal sector workers can protect the vulnerable from falling into extreme poverty. By taking advantage of increased digitalization and mobile money services, governments can provide relief to informal workers quickly and at reduced cost. Lastly, public information campaigns are crucial to securing the population’s buy-in and boosting the effectiveness of anti-pandemic measures. &nbsp;</p>



<p>As the rollout of vaccines slowly proceeds, the AfDB will support countries in implementing the AEO’s policy recommendations. That way, Africa can simultaneously save lives and protect livelihoods.</p>



<p>– <em>By Dr Hanan Morsy and Dr Adamon Mukasa; Morsy is the Director of the Macroeconomic Policy, Forecasting and Research Department at the African Development Bank, and Mukasa is Senior Research Economist in the same department.</em></p>


DRCONGO-HEALTH-VIRUS-EDUCATION

How Effective Are Lockdowns In Africa?


<p><strong>TOPLINE </strong>AstraZeneca on Tuesday announced its monoclonal antibody treatment for Covid-19 did not meet the primary goal of preventing symptoms in people who have been exposed to the coronavirus, denting hopes of a new therapeutic treatment for Covid-19 for unvaccinated people.</p>



<h3 id="h-key-facts">KEY FACTS</h3>



<p>The antibody therapy, AZD7442, reduced the risk of developing symptomatic Covid-19 by only 33% among all exposed patients—including those who tested negative after exposure—compared to a placebo, which was deemed to be statistically insignificant, the company&nbsp;<a href="https://www.astrazeneca.com/content/astraz/media-centre/press-releases/2021/update-on-azd7442-storm-chaser-trial.html" target="_blank" rel="noreferrer noopener">announced</a>&nbsp;in a release.</p>



<p>The data was gathered from the company’s Phase III trials which were conducted on unvaccinated adults older than 18 years with confirmed exposure to a person with Covid-19 within the previous eight days.</p>



<p>The antibody therapy, however, was 92% effective in preventing symptomatic Covid-19 compared to the placebo in patients who tested negative after exposure, suggesting that the drug may be effective in preventing symptoms in people who are not already infected.</p>



<p>The drug continues to be tested as possible prophylaxis against Covid-19 in other trials, the company noted.</p>



<h3 id="h-crucial-quote">CRUCIAL QUOTE</h3>



<p>The trial’s principal investigator, Dr. Myron J. Levin, noted that the drug may be effective in preventing symptomatic Covid-19 in people who are not yet infected, adding: “While Covid-19 vaccination efforts have been successful, there is still a significant need for prevention and treatment options for certain populations, including those unable to be vaccinated or those who may have an inadequate response to vaccination.”</p>



<h3 id="h-what-to-watch-for">WHAT TO WATCH FOR</h3>



<p>AstraZeneca’s AZD7442 was developed with support from the U.S. government. In March, the company announced that it had inked a deal with the government to supply up to half a million doses of AZD7442 for $205 million—subject to the drug receiving emergency use authorization from the U.S. Food and Drug Administration. The company said it is continuing to discuss its next steps with the U.S. government.</p>



<h3 id="h-key-background">KEY BACKGROUND</h3>



<p>While several effective vaccines have been developed to protect against Covid-19, effective drugs against the disease remain sparse. Similar monoclonal antibody treatments developed by Regeneron Pharmaceuticals and Eli Lilly have been authorized for use in the U.S., but supplies of the drugs remain limited. The development of therapeutics that prevent symptomatic Covid-19 is critical to ending the pandemic as vaccines are yet to be accessible to large swathes of the world’s population.</p>



<h3 id="h-further-reading">FURTHER READING</h3>



<p><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/astrazeneca-says-its-antibody-treatment-failed-in-preventing-covid-19-exposed-2021-06-15/" target="_blank" rel="noreferrer noopener">AstraZeneca says its antibody treatment failed in preventing COVID-19 in exposed patients</a>&nbsp;(Reuters)</p>



<p><a href="https://www.marketwatch.com/story/astrazeneca-azd7442-trial-for-prevention-of-symptomatic-covid-19-didn-t-meet-primary-goal-271623738254" target="_blank" rel="noreferrer noopener">AZD7442 Trial for Prevention of Symptomatic Covid-19 Didn&#8217;t Meet Primary Goal</a> (MarketWatch)</p>



<p><strong><em>By Siladitya Ray, Forbes Staff</em></strong></p>


Kenya Vaccinates Elderly Against Covid-19

AstraZeneca’s Covid-19 Antibody Treatment Failed To Prevent Symptoms In Exposed Individuals


<p><strong>TOPLINE</strong> Three researchers working at a Wuhan virology lab went to the hospital with Covid-like symptoms weeks before the first Covid-19 case was confirmed in China on December 8, according to newly disclosed U.S. intelligence obtained and reported by the Wall Street Journal on Sunday—corroborating previous State Department findings and casting further doubts on the longstanding assertion that Covid-19 did not escape from a lab.</p>



<h3 id="h-key-facts">KEY FACTS</h3>



<p>The State Department previously&nbsp;<a href="https://2017-2021.state.gov/fact-sheet-activity-at-the-wuhan-institute-of-virology/index.html" target="_blank" rel="noreferrer noopener">reported</a>&nbsp;that U.S. officials have &#8220;reason to believe&#8221; several researchers inside the Wuhan Institute of Virology faced &#8220;symptoms consistent with both COVID-19 and common seasonal illnesses&#8221; last fall, but it didn&#8217;t specify that the researchers were hospitalized or the exact timing of their illnesses.</p>



<p>Unnamed officials familiar with the intelligence reportedly gave the&nbsp;<em>Wall Street Journal</em>&nbsp;varying accounts of the new information&#8217;s veracity, with one person saying it needed further investigation while another described it as &#8220;very precise.&#8221;</p>



<p>“The U.S. continues to hype the lab leak theory,&#8221; China&#8217;s Foreign Ministry, which did not immediately respond to&nbsp;<em>Forbes&#8217;&nbsp;</em>requestfor comment, said in a statement to the&nbsp;<em>Wall Street Journal</em>.&nbsp;</p>



<p>In its statement, the Foreign Ministry pointed to March&nbsp;<a href="https://www.who.int/docs/default-source/coronaviruse/who-convened-global-study-of-origins-of-sars-cov-2-china-part-annexes.pdf?sfvrsn=3065bcd8_5" target="_blank" rel="noreferrer noopener">findings</a>&nbsp;from the World Health Organization saying it was &#8220;extremely unlikely&#8221; that Covid-19 originated from a lab leak and that it was instead more likely the virus spread from bats to humans.</p>



<p>However, after the report was released, WHO head Tedros Ghebreyesus called for a deeper investigation on the matter,&nbsp;<a href="https://www.bloomberg.com/news/articles/2021-03-30/who-chief-critiques-covid-report-says-lab-leak-study-needed" target="_blank" rel="noreferrer noopener">saying</a>&nbsp;the probe didn’t adequately assess the possibility of a lab leak.</p>



<p><em>Forbes</em>&nbsp;is awaiting comment from the State Department.</p>



<h2 id="h-key-background">KEY BACKGROUND</h2>



<p>Many scientists last year&nbsp;<a href="https://www.forbes.com/sites/jackbrewster/2020/05/10/a-timeline-of-the-covid-19-wuhan-lab-origin-theory/?sh=370c029e5aba">initially dismissed</a>&nbsp;claims that Covid-19 originated in a Wuhan lab, but the theory quickly became a hot-button issue among conservative lawmakers casting blame onto China for the pandemic. However, as widespread vaccination helps the U.S. turn a corner on the virus, a growing number of domestic officials—from both sides of the aisle—are once again calling for investigations into the origins of Covid-19. Secretary of State Antony Blinken&nbsp;<a href="https://www.forbes.com/sites/jonathanponciano/2021/04/11/biden-secretary-of-state-condemns-chinas-acts-of-genocide-against-muslim-uyghurs/?sh=26f49b7050ca">condemned</a>&nbsp;China last month for its lack of transparency during the pandemic&#8217;s early days, saying the country failed to give international health experts real-time access to information about the virus&#8217; spread and urging the country to help put in place a stronger global health security system to revisit the pandemic&#8217;s origins.</p>



<h3 id="h-surprising-fact">SURPRISING FACT</h3>



<p>Though the virus was first confirmed in December 2019, WHO researchers have since&nbsp;<a href="https://www.wsj.com/articles/possible-early-covid-19-cases-in-china-emerge-during-who-mission-11612996225" target="_blank" rel="noreferrer noopener">identified</a>&nbsp;more than 90 potential Covid-19 cases dating as far back as October of that year.</p>



<h3 id="h-crucial-quote">CRUCIAL QUOTE&nbsp;</h3>



<p>Asked earlier this month whether he was confident Covid-19 developed naturally, Dr. Anthony Fauci, one of the nation&#8217;s top infectious disease experts,&nbsp;<a href="https://www.foxnews.com/politics/fauci-not-convinced-covid-19-developed-naturally" target="_blank" rel="noreferrer noopener">responded</a>: &#8220;No actually&#8230; I am not convinced about that. I think we should continue to investigate what went on in China until we continue to find out to the best of our ability what happened… Certainly, the people who investigated it say it likely was the emergence from an animal reservoir that then infected individuals, but it could have been something else, and we need to find that out.”</p>



<h3 id="h-further-reading">FURTHER READING</h3>



<p><a href="https://www.wsj.com/articles/intelligence-on-sick-staff-at-wuhan-lab-fuels-debate-on-covid-19-origin-11621796228?reflink=share_mobilewebshare" target="_blank" rel="noreferrer noopener">Intelligence on Sick Staff at Wuhan Lab Fuels Debate On Covid-19 Origin</a>&nbsp;<em>(WSJ)</em></p>



<p><a href="https://www.forbes.com/sites/jackbrewster/2020/05/10/a-timeline-of-the-covid-19-wuhan-lab-origin-theory/">A Timeline Of The COVID-19 Wuhan Lab Origin Theory</a> <em>(Forbes)</em></p>



<p><strong><em>By Jonathan Ponciano, Forbes Staff</em></strong></p>


gettyimages-1201569878-594×594

Report: Wuhan Lab Staff Went To Hospital With Covid-Like Symptoms Before Confirmed Outbreak, New Intelligence Finds


<p id="h-topline"><strong>TOPLINE</strong> A new U.K. study has found that more than 95% of Britons vaccinated with just one shot of the Pfizer or AstraZeneca vaccine develop Covid-19 antibodies, a figure that rises to almost 100% after the second dose, adding to mounting evidence from the real-world deployment of the vaccines that show they are effective and useful tools in bringing the pandemic under control. </p>



<h3 id="h-key-facts">KEY FACTS</h3>



<p>In a study of more than 8,500 people from England and Wales, who did not have antibodies before their first shot and provided a total of 13,232 antibody samples, 96% developed antibodies 28 to 34 days after receiving their first dose, according to research from University College London (UCL).</p>



<p>The&nbsp;<a href="https://ucl-virus-watch.net/?page_id=913" target="_blank" rel="noreferrer noopener">research</a>, which is being prepared for peer review, found this figure to rise to 99% within seven and 14 days of their second shot for recipients of both vaccines, evidence that they provide protection against the coronavirus.&nbsp;</p>



<p>While those receiving the Pfizer-BioNTech vaccine developed antibodies faster than those receiving the AstraZeneca shot, rates were practically identical after a period of four weeks.&nbsp;&nbsp;</p>



<p>Many groups at a greater risk from Covid-19—including those with underlying conditions like diabetes and cancer, those taking immune system suppressing drugs and older adults—produced fewer antibodies after a single dose, a potential problem for countries like the U.K. where the second dose is&nbsp;<a href="https://www.forbes.com/sites/siladityaray/2021/05/14/study-finds-12-week-gap-between-pfizer-covid-19-vaccine-dose-generates-35-times-higher-antibody-response/?sh=5fe5400da6a3">delayed</a>&nbsp;by several weeks in order to vaccinate more people.</p>



<p>However, a second shot boosted antibody levels to the standard high levels, something Professor Rob Aldridge, the chief investigator of the study,&nbsp;<a href="https://www.theguardian.com/world/2021/may/18/96-of-britons-develop-antibodies-after-one-covid-jab-study-finds" target="_blank" rel="noreferrer noopener">told</a>&nbsp;the&nbsp;<em>Guardian</em>&nbsp;underscores the “importance of getting the second dose.”&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>



<p>Aldridge described the findings as “reassuring &#8211; vaccines are our way out of the pandemic.”</p>



<h3 id="h-crucial-quote">CRUCIAL QUOTE</h3>



<p>Dr. Maddie Shrotri, the paper’s lead author,&nbsp;<a href="https://www.theguardian.com/world/2021/may/18/96-of-britons-develop-antibodies-after-one-covid-jab-study-finds" target="_blank" rel="noreferrer noopener">said</a>&nbsp;the findings are from some of the earliest “real-world vaccine studies in the U.K.” Shrotri said the results are “fantastic news,” adding that it is “remarkable” how well the vaccines work given the speed at which they’ve been developed. “It’s a real feat of science in the face of the most devastating pandemic in a century.”</p>



<h3 id="h-big-number">BIG NUMBER</h3>



<p>57 million. This is&nbsp;<a href="https://coronavirus.data.gov.uk/details/vaccinations" target="_blank" rel="noreferrer noopener">how many vaccines&nbsp;</a>have been given out in the U.K., the vast majority being the Pfizer-BioNTech or AstraZeneca shots. Just over 20 million people have received their second dose.&nbsp;</p>



<h3 id="h-further-reading">FURTHER READING</h3>



<p><a href="https://www.theguardian.com/world/2021/may/18/96-of-britons-develop-antibodies-after-one-covid-jab-study-finds" target="_blank" rel="noreferrer noopener">Covid vaccine: 96% of Britons develop antibodies after one jab, study finds</a>&nbsp;(Guardian)</p>



<p><a href="https://www.forbes.com/sites/siladityaray/2021/05/14/study-finds-12-week-gap-between-pfizer-covid-19-vaccine-dose-generates-35-times-higher-antibody-response/?sh=5fe5400da6a3">12-Week Gap Between Pfizer Vaccine Doses Generates Higher Antibody Response, Study Finds</a>&nbsp;(Forbes)</p>


Healthcare professional in protective gloves & workwear holding & organising a tray of COVID-19 vaccine vials

96% Of People Develop Covid Antibodies After Just One Shot Of Pfizer Or AstraZeneca Vaccine, U.K. Study Finds


<p id="h-topline"><strong>TOPLINE</strong> As India continues to face a devastating second wave of the pandemic, the World Health Organisation on Monday classified the coronavirus variant first detected in the country–B.1.617—as a variant of concern following preliminary findings which suggest it could be more transmissible.</p>



<h3 id="h-key-facts">KEY FACTS</h3>



<p>The WHO’s new classification—which is an upgrade from “variant of interest”—adds the Indian variant to a list that also contains variants first detected in the U.K. (B.1.1.7), South Africa (B.1.351) and&nbsp; Brazil (P.1).</p>



<p>The global health body will publish a detailed report on the B.1.617 variant in its weekly epidemiological update on Tuesday, the WHO’s technical lead officer on Covid-19, Maria van Kerkhove said.</p>



<p>Kerkhove noted that some available information suggested that the variant showed “increased transmissibility,” and a non-peer-reviewed study on a limited number of patients also suggested that it may also be able to evade some key antibodies.</p>



<h3 id="h-big-number">BIG NUMBER</h3>



<p>3,876. That’s the total number of Covid-19 deaths India&nbsp;<a href="https://twitter.com/COVIDNewsByMIB/status/1391986229768376322" target="_blank" rel="noreferrer noopener">reported</a>&nbsp;on Tuesday, taking its official tally up to 249,992—which many experts suggest is a severe undercount. The country’s daily infection and fatalities have continued to remain high despite a drop in new infections in key cities like Mumbai and Delhi.</p>



<h3 id="h-key-background">KEY BACKGROUND</h3>



<p>The second wave of the pandemic has continued to rage across India pushing the country’s health care system past its breaking point. As the country reports more than 350,000 new infections and nearly 4,000 deaths from Covid-19 every day, the country’s Prime Minister Narendra Modi and his government are under increasing pressure to impose a strict nationwide lockdown. Rahul Gandhi, the leader of India’s main opposition party has written a letter to Modi which slams his government’s failures and notes that “another devastating national lockdown is almost inevitable.”&nbsp;<a href="https://www.dnaindia.com/india/report-lockdown-in-india-latest-news-may-8-pressure-mounts-on-pm-narendra-modi-to-impose-nationwide-lockdown-shutdown-coronavirus-latest-news-2889434" target="_blank" rel="noreferrer noopener">Several others</a>, including medical experts, Supreme Court judges and other opposition leaders and even&nbsp;<a href="https://qz.com/india/2007013/anthony-fauci-and-indian-doctors-ask-modi-to-declare-a-lockdown/" target="_blank" rel="noreferrer noopener">Dr. Anthony Fauci</a>—the U.S.’s senior-most infectious disease official—have called for a national shut down to break the chain of transmission.&nbsp;</p>



<h3 id="h-further-reading">FURTHER READING</h3>



<p><a href="https://www.bloomberg.com/news/articles/2021-05-10/who-cites-concern-on-variant-from-india-seen-spreading-quickly?utm_source=twitter&amp;utm_medium=social&amp;utm_campaign=socialflow-organic&amp;utm_content=business&amp;cmpid=socialflow-twitter-business&amp;sref=CSMHWBLp" target="_blank" rel="noreferrer noopener">Covid Variant From India Triggers WHO Concern Over Fast Spread</a>&nbsp;(Bloomberg)</p>



<p><strong><a href="https://www.forbes.com/coronavirus/">Full coverage and live updates on the Coronavirus</a></strong></p>



<p><strong><em>By Siladitya Ray, Forbes Staff</em></strong></p>


INDIA-HEALTH-VIRUS-VACCINES

WHO Classifies Indian Covid-19 Mutation As A ‘Variant Of Concern’


<p><strong>Topline</strong>: South Africa’s President Cyril Ramaphosa announced in another “family meeting” on Tuesday evening that although the country will not be moving from Alert Level one, heavy restrictions would be put in place for this upcoming Easter Weekend.  </p>



<p><strong>Key Facts</strong>&nbsp;</p>



<ul><li>Officially it has been over a year since South African president, Cyril Ramaphosa, announced that country would be going into a hard lockdown to mitigate the spread of the global pandemic, Covid-19.  </li><li>However, the president made it clear that the number of cases has remained “relatively stable” but warns the country should not be complacent.  </li><li>“The number of hospitalizations is declining, as is the number of deaths. Our national recovery rate stands at slightly higher than 95%,” Ramaphosa said in his address.  </li><li>With that being said, alcohol sales for this weekend will be restricted to curb “reckless behavior” over the long weekend. On-site sales at restaurants, shebeens, and bars will still be allowed but just up until 23:00. </li><li>In addition to that, Ramaphosa also announced that South Africa has secured another 20 million dosages of the Johnson &amp; Johnson vaccine. In the middle of February, South Africa began Phase 1 of its vaccination program, which involves the vaccination of health workers. This phase is on track to be completed within three months. Phase 2 is scheduled to start in mid-May. </li></ul>



<p><strong>Crucial Quote</strong></p>



<p>“Any action that puts ourselves or others at risk must be avoided. The restrictions that are in place for our collective health and safety must be observed. Let us be a responsible nation that is forever aware of the presence of the virus. Let us remain at home or in small groups. Let us avoid being in large crowds and places with poor ventilation. Let us not go to funerals unless we are immediate family and not visit the homes of the bereaved. We all have a role in this great national effort to end COVID-19,” Ramaphosa pleaded with South Africa.&nbsp;</p>


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